EGFR-IN-107 | MedChemExpress (MCE)

EGFR-IN-107 (compound 3r) is an orally active EGFR inhibitor with IC50 values of 0.4333 μM for EGFRWT and 0.0438 μM for EGFRL858R/T790M. EGFR-IN-107 has anti-proliferative activity and can inhibit the proliferation of H1975 cells and induce their apoptosis. EGFR-IN-107 can be used in cancer research[1].

Trivial name EGFR-IN-107
Catalog Number HY-163396
Research Area Cancer
Purity ≥98.0%
SMILES C=CC(NC1=C(C=C(C(NC2=NC(C3=C(N(C4=C3C=CC=C4)C)C5=CC=CC(F)=C5)=CC=N2)=C1)OC)N(CCN(C)C)C)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/egfr-in-107.html