PLK1/BRD4-IN-5 | MedChemExpress (MCE)

PLK1/BRD4-IN-5 (Compound SC10) is an orally active PLK1 and BRD4 inhibitor with IC50 values of 0.3  nM and 60.8  nM, respectively. PLK1/BRD4-IN-5 can induce MV4-11 cell block in S phase and apoptosis) in a dose-dependent manner. PLK1/BRD4-IN-5 can be used in cancer research[1].

Trivial name PLK1/BRD4-IN-5
Catalog Number HY-158031
Research Area Cancer
Purity ≥98.0%
SMILES CC[C@@H]1C(N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C5C(CCN5C(CN6C[C@@H](N[C@@H](C6)C)C)=O)=C4)OC)C)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/plk1-brd4-in-5.html