HPK1-IN-43 | MedChemExpress (MCE)

HPK1-IN-43 (compound 9f) is a HPK1 kinase inhibitor with the IC50 value of 0.32 nM. HPK1-IN-43 inhibits the phosphorylation of the downstream protein SLP-76 and enhances the secretion of interleukin-2 (IL-2) and interferon-γ (IFN-γ). HPK1-IN-43 can be used in cancer research[1].

Trivial name HPK1-IN-43
Catalog Number HY-161335
Research Area Cancer
Purity ≥98.0%
SMILES O=C1N(CC2=C(C(F)(F)F)C=CC=C2)C3=NC(NC4=C(OC)C=C(CCN(C)C5)C5=C4)=NC=C3C(N)=C1
Size 1 mg
Supplier Page https://www.medchemexpress.com/hpk1-in-43.html