HER2-IN-16 | MedChemExpress (MCE)
HER2-IN-16 (Compound 14) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-16 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC)[1].
| Trivial name | HER2-IN-16 |
| Catalog Number | HY-163420 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | C=CC(NC1CN(C1)C2=C3C(NC4=CC(C)=C(C=C4)OC5=CC6=NC=NN6C=C5)=NC=NN3C=C2)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/her2-in-16.html |