Leteprinim | MedChemExpress (MCE)

Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species[1][2][3][4].

Trivial name Leteprinim
Catalog Number HY-120251
Alternative Name(s) AIT-082 free acid
Research Area Neurological Disease
CAS# 138117-50-7
Purity ≥98.0%
SMILES O=C(O)C1=CC=C(NC(CCN2C=NC3=C2NC=NC3=O)=O)C=C1
Size 1 mg
Supplier Page https://www.medchemexpress.com/leteprinim.html