Cofetuzumab pelidotin | MedChemExpress (MCE)
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research[1][2][3].
Trivial name | Cofetuzumab pelidotin |
Catalog Number | HY-P99829 |
Alternative Name(s) | PF-06647020; ABBV-647; h6M24-vc0101 |
Research Area | Cancer |
CAS# | 1869937-48-3 |
Purity | 99.7% |
SMILES | [Cofetuzumab pelidotin] |
Size | 10 mg |
Supplier Page | https://www.medchemexpress.com/cofetuzumab-pelidotin.html |