Tepotinib | MedChemExpress (MCE)
Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation. Tepotinib has antitumor effects[1][2][3].
| Trivial name | Tepotinib |
| Catalog Number | HY-14721 |
| Alternative Name(s) | EMD-1214063 |
| Research Area | Cancer |
| CAS# | 1100598-32-0 |
| Purity | 99.9% |
| SMILES | N#CC1=CC=CC(C(C=CC2=O)=NN2CC3=CC=CC(C4=NC=C(C=N4)OCC5CCN(CC5)C)=C3)=C1 |
| Size | 5 mg |
| Supplier Page | https://www.medchemexpress.com/EMD-1214063.html |