Antitumor agent-143 | MedChemExpress (MCE)
Antitumor agent-143 (compound 2c) is an antitumor agent that blocks cell proliferation of A549 cells during the S phase and induces an early apoptosis. Antitumor agent-143 induces cell death via ferroptosis, apoptosis by a ROS-mediated mitochondrial dysfunction pathway and GSDMD-mediated pyroptosis[1].
| Trivial name | Antitumor agent-143 |
| Catalog Number | HY-161332 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | F[P-](F)(F)(F)(F)F.NC(N=C1Cl)=NC(Cl)=C1C(N2)=NC3=C2C(C=CC=[N]45)=C5C6=C3C=CC=[N]6[Ir]74([N]8=C9C(C=CC=C%10)=C%10C=C8)(C%11=C9C=CC=C%11)[N]%12=C(C%13=CC=CC=C%137)C%14=C(C=CC=C%14)C=C%12 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/antitumor-agent-143.html |