PKM2-IN-6 | MedChemExpress (MCE)
PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer[1].
| Trivial name | PKM2-IN-6 |
| Catalog Number | HY-157913 |
| Research Area | Cancer |
| CAS# | 771467-00-6 |
| Purity | ≥98.0% |
| SMILES | COC1=CC=CC=C1NC2=NC(C3=CN=C4C=CC=CN43)=CS2 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/pkm2-in-6.html |