HDAC6-IN-34 | MedChemExpress (MCE)
HDAC6-IN-34 (compound 21) is an oral active and selective HDAC6 inhibitor with the IC50 of 18 nM. HDAC6-IN-34 increases the acetylation level of tubulin without affecting histone acetylation in cutaneous T-cell lymphoma cells and inhibits TNF-α secretion in LPS (HY-D1056)-stimulated macrophage cells. HDAC6-IN-34 shows excellent anti-arthritic efficacy in rat[1].
Trivial name | HDAC6-IN-34 |
Catalog Number | HY-163368 |
Research Area | Inflammation/Immunology |
CAS# | 1432508-73-0 |
Purity | ≥98.0% |
SMILES | CC1(CC(C2=C(N(N=C2C(F)(F)F)CC3=CC=C(C=C3)C(NO)=O)C1)=O)C |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/hdac6-in-34.html |