PROTAC HPK1 Degrader-1 | MedChemExpress (MCE)

PROTAC HPK1 Degrader-1 (Compound B1) is a potent HPK1 degrader with DC₅₀ value of 1.8 nM. PROTAC HPK1 Degrader-1 inhibits phosphorylation of the SLP76 protein with IC₅₀ value of 496.1 nM. PROTAC HPK1 Degrader-1 is a bona fide HPK1-PROTAC degrader, which provided a potential tool for further HPK1 investigation in TCR signaling^[1].

Price Not Available 1 mg PROTAC HPK1 Degrader-1 | MedChemExpress (MCE) Supplier Page

Trivial name	PROTAC HPK1 Degrader-1
Catalog Number	HY-163372
Research Area	Cancer
Purity	≥98.0%
SMILES	O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCC(N4CCN(C5=CC=C(C6=CN=C(NC=C7C8=CC=C(OC)C(OC)=C8)C7=C6)C=C5)CC4)=O)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/protac-hpk1-degrader-1.html