HMC-B17 | MedChemExpress (MCE)

HMC-B17 is a selective, orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that potentiates anti-PD-L1 efficacy. HMC-B17 potently enhances the IL-2 secretion in Jurkat cells (EC50 = 11.56 nM). HMC-B17 can be used for the research of cancer[1].

Trivial name HMC-B17
Catalog Number HY-157838
Research Area Cancer
CAS# 2935913-83-8
Purity ≥98.0%
SMILES COC1=C(C=C(C=C1)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C5CCN(C)CC5)OC
Size 1 mg
Supplier Page https://www.medchemexpress.com/hmc-b17.html