HMC-B17 | MedChemExpress (MCE)
HMC-B17 is a selective, orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that potentiates anti-PD-L1 efficacy. HMC-B17 potently enhances the IL-2 secretion in Jurkat cells (EC50 = 11.56 nM). HMC-B17 can be used for the research of cancer[1].
| Trivial name | HMC-B17 |
| Catalog Number | HY-157838 |
| Research Area | Cancer |
| CAS# | 2935913-83-8 |
| Purity | ≥98.0% |
| SMILES | COC1=C(C=C(C=C1)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C5CCN(C)CC5)OC |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/hmc-b17.html |