NF-κB-IN-15 | MedChemExpress (MCE)
NF-κB-IN-15 (compound 14r) is a potent NF-κB inhibitor. NF-κB-IN-15 decreases the NO levels and inhibits the release of IL-6, TNF-α, and IL-1β in LPS (HY-D1056) -induced cells. NF-κB-IN-15 inhibits LPS-induced phosphorylation of p65 and degradation of IκBα. NF-κB-IN-15 shows anti-inflammatory activity has the potential for the research of acute lung injury (ALI)[1].
| Trivial name | NF-κB-IN-15 |
| Catalog Number | HY-162316 |
| Research Area | Inflammation/Immunology |
| Purity | ≥98.0% |
| SMILES | CC1=C(C)C=CC=C1N2CCN(C([C@H](CC3=CC(OC)=C(O)C(OC)=C3)[C@@H](C(N4CCN(C5=CC=CC(C)=C5C)CC4)=O)CC6=CC(OC)=C(O)C(OC)=C6)=O)CC2 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/nf-κb-in-15.html |