Keap1-Nrf2-IN-18 | MedChemExpress (MCE)
Keap1-Nrf2-IN-18 (Compound 22) is an orally active Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with good pharmacokinetics (PK) profiles and more potent in vivo activities in rats. Keap1-Nrf2-IN-18 has the strongest inhibitory activity in structure−activity relationship (SAR) study (KD = 0.0029 μM)[1].
| Trivial name | Keap1-Nrf2-IN-18 |
| Catalog Number | HY-157928 |
| Research Area | Inflammation/Immunology |
| Purity | ≥98.0% |
| SMILES | CC1=CC=C([C@@H](NC([C@H](C2=CC=C(CC3=NC=CC=C3OCC)C=C2)F)=O)[C@@H](C)C(O)=O)C=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/keap1-nrf2-in-18.html |