SHP2-IN-26 | MedChemExpress (MCE)

SHP2-IN-26 (Compound 4b) is a highly selective SHP2 allosteric inhibitor with a IC50 value of 3.2 nM. SHP2-IN-26 inhibits the phosphorylation of ERK and AKT in NCI-H358 cells. SHP2-IN-26 has antitumor activity[1].

Trivial name SHP2-IN-26
Catalog Number HY-157888
Research Area Cancer
Purity ≥98.0%
SMILES N[C@@H]1[C@H](C)OCC12CCN(C3=CN=C4C(NN=C4SC5=CC=CC(Cl)=C5Cl)=N3)CC2
Size 1 mg
Supplier Page https://www.medchemexpress.com/shp2-in-26.html