(R)-NX-2127 | MedChemExpress (MCE)
(R)-NX-2127 (compound 28) is an orally active Bruton’s Tyrosine Kinase (Btk) degrader. (R)-NX-2127 degrades IKZF1 and IKZF3 by molecular glue interactions with the cereblon E3 ubiquitin ligase complex[1].
| Trivial name | (R)-NX-2127 |
| Catalog Number | HY-153220A |
| Research Area | Inflammation/Immunology; Cancer |
| CAS# | 3024312-52-2 |
| Purity | ≥98.0% |
| SMILES | O=C1C2=CC(N3C[C@@H](CN4CCC(C5=CC=C(C=C5)NC6=C(N=CC(N7CCCCC7)=N6)C(N)=O)CC4)CC3)=CC=C2C(N1C8C(NC(CC8)=O)=O)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/r-nx-2127.html |