EZH2/HSP90-IN-29 | MedChemExpress (MCE)
EZH2/HSP90-IN-29 is a dual inhibitor for EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively. EZH2/HSP90-IN-29 increases apoptosis/necrosis-related gene expression, induces cell cycle arrest at M phase and inhibits reactive oxygen species (ROS) catabolism pathway. EZH2/HSP90-IN-29 is able to cross the blood-brain-barrier (BBB)[1].
| Trivial name | EZH2/HSP90-IN-29 |
| Catalog Number | HY-163288 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | O=C(NCC1=C(C=C(NC1=O)C)C)C2=CC(C3=CC=CC(N(C(C4=CC(C(C)C)=C(C=C4O)O)=O)C)=C3)=CC(N(C5CCOCC5)CC)=C2C |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/ezh2-hsp90-in-29.html |