QC-182 | MedChemExpress (MCE)

QC-182 is a potent PROTAC degrader of p300/CBP. QC-182 reduces p300 protein in the SK-HEP-1 cells (DC₅₀ = 93nM). QC-182 potently and effectively inhibits cell growth in the SK-HEP-1 and JHH7 cell lines with IC₅₀ values of 0.733 and 0.477 μM, respectively. QC-182 can be used for the research of hepatocellular carcinoma (HCC)^[1].

Price Not Available 1 mg QC-182 | MedChemExpress (MCE) Supplier Page

Trivial name	QC-182
Catalog Number	HY-162259
Research Area	Cancer
Purity	≥98.0%
SMILES	O=C1N(C2C(NC(CC2)=O)=O)C(C(C1=C3)=CC=C3N(C4)CC4N5CCC(N6C7=CC=C(C8=C(C)ON=C8C)C=C7N=C6[C@H]9N(C%10=CC(F)=C(F)C=C%10)C(CCC9)=O)CC5)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/qc-182.html