SARS-CoV-2-IN-81 | MedChemExpress (MCE)
SARS-CoV-2-IN-81 (compound 12e) is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection[1].
| Trivial name | SARS-CoV-2-IN-81 |
| Catalog Number | HY-161261 |
| Research Area | Infection |
| Purity | ≥98.0% |
| SMILES | C12=CC(C3=CN=C(NC=C4C#CC5=CN=CC=C5)C4=C3)=CC=C1N(CCOC6)C6CO2 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/sars-cov-2-in-81.html |