JAK1/2-IN-1 | MedChemExpress (MCE)
JAK1/2-IN-1 is a potent JAK1 and JAK2 inhibitor with IC50 values of 0.4 nM and 8.1 nM, respectively. JAK1/2-IN-1 also inhibits IL-4 and IL-13 with IC50s of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a)[1].
| Trivial name | JAK1/2-IN-1 |
| Catalog Number | HY-162248 |
| Research Area | Inflammation/Immunology; Cancer |
| CAS# | 3023876-01-6 |
| Purity | ≥98.0% |
| SMILES | CC1=C(N=C(NC2=CC(C(F)(F)F)=C3C(COB3O)=C2)N=C1)N[C@H]4[C@H](C#N)CCOC4 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/jak1-2-in-1.html |