Lck-IN-2 | MedChemExpress (MCE)

Lck-IN-2 (compound 12a) is an inhibitor of Lymphocyte-specific protein tyrosine kinase (Lck) with IC50 of 10.6 nM. Lck-IN-2 reveals efficacy in colon cancer cells with GI50s of 0.24-1.26 μM. Lck-IN-2 exhibits an apoptotic effect in Colo201 cells[1].

Trivial name Lck-IN-2
Catalog Number HY-163278
Research Area Cancer
CAS# 2615173-24-3
Purity ≥98.0%
SMILES CC1=CC=C(C=C1N2CC3=C(N(C2=O)C)N=C(N=C3)NC4=CN=C(C=C4)C)NC(C5=CC=C(C(OCC(C)C)=C5)[N+]([O-])=O)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/lck-in-2.html