Amelparib hydrochloride | MedChemExpress (MCE)
Amelparib (JPI-289) hydrochloride is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib hydrochloride inhibits PARP-1 activity (IC50 = 18.5 nM) and cellular PAR formation (IC50 = 10.7 nM). Amelparib hydrochloride is a potential neuroprotective agent. Amelparib hydrochloride has the potential for the research of acute ischaemic stroke[1].
| Trivial name | Amelparib hydrochloride |
| Catalog Number | HY-116218C |
| Alternative Name(s) | JPI-289 hydrochloride |
| Research Area | Neurological Disease; Cardiovascular Disease |
| Purity | 98.4% |
| SMILES | O=C1NC2=C(C3=C1CCCN3)C(OCC)=CC(CN4CCOCC4)=C2.Cl |
| Size | 5 mg |
| Supplier Page | https://www.medchemexpress.com/amelparib-hydrochloride.html |