PF-06821497 | MedChemExpress (MCE)
PF-06821497 (compound 23a) is a potent, selective and orally active Enhancer of Zeste Homolog 2 (EZH2) inhibitor, with a Ki value <0.1 nM against mutant Y641N EZH2. Exhibits robust tumor growth inhibition[1].
| Trivial name | PF-06821497 |
| Catalog Number | HY-101571A |
| Research Area | Cancer |
| CAS# | 1844849-10-0 |
| Purity | 99.1% |
| SMILES | O=C1N(CC2=C(OC)C=C(C)NC2=O)CCC3=C1C(Cl)=C([C@H](OC)C4COC4)C=C3Cl |
| Size | 25 mg |
| Supplier Page | https://www.medchemexpress.com/pf-06821497.html |