Tegaserod-d11 | MedChemExpress (MCE)
Tegaserod-d11 is deuterated labeled Tegaserod (HY-14153). Tegaserod is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research[1][2][3].
| Trivial name | Tegaserod-d11 |
| Catalog Number | HY-14153S |
| Research Area | Metabolic Disease; Cancer |
| CAS# | 1134188-56-9 |
| Purity | ≥98.0% |
| SMILES | N=C(NC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])N/N=C/C1=CNC2=CC=C(OC)C=C21 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/tegaserod-d11.html |