Lenalidomide-13C5,15N | MedChemExpress (MCE)

Lenalidomide-13C5,15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].

Trivial name Lenalidomide-13C5,15N
Catalog Number HY-A0003S2
Alternative Name(s) CC-5013-13C5,15N
Research Area Inflammation/Immunology; Cancer
Purity ≥98.0%
SMILES O=C1C2=CC=CC(N)=C2C[15N]1[13CH]([13C](N3)=O)[13CH2][13CH2][13C]3=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/lenalidomide-13c5-15n.html