Lenalidomide-13C5,15N | MedChemExpress (MCE)
Lenalidomide-13C5,15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
Trivial name | Lenalidomide-13C5,15N |
Catalog Number | HY-A0003S2 |
Alternative Name(s) | CC-5013-13C5,15N |
Research Area | Inflammation/Immunology; Cancer |
Purity | ≥98.0% |
SMILES | O=C1C2=CC=CC(N)=C2C[15N]1[13CH]([13C](N3)=O)[13CH2][13CH2][13C]3=O |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/lenalidomide-13c5-15n.html |