Hydrochlorothiazide-15N2,13C,d2 | MedChemExpress (MCE)
Hydrochlorothiazide-15N2,13C,d2 is 15N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].
| Trivial name | Hydrochlorothiazide-15N2,13C,d2 |
| Catalog Number | HY-B0252S3 |
| Alternative Name(s) | HCTZ-15N2,13C,d2 |
| Research Area | Metabolic Disease; Cardiovascular Disease; Cancer |
| CAS# | 2140316-81-8 |
| Purity | ≥98.0% |
| SMILES | O=S(C1=C(Cl)C=C(C2=C1)N[13C]([2H])([2H])[15NH]S2(=O)=O)([15NH2])=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/hydrochlorothiazide-15n2-13c-d2.html |