ML-SA1
ML-SA1 (Mucolipin synthetic agonist 1) is an activator of TRPML channels. ML-SA1 also inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 values of ML-SA1 against DENV2 RNA and ZIKV RNA are 8.93 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral.
| Trivial name | Mucolipin synthetic agonist 1 |
| Catalog Number | S9926 |
| Molecular Formula | C22H22N2O3 |
| CAS# | 332382-54-4 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CC1CC(C)(C)N(C(=O)CN2C(=O)C3=C(C=CC=C3)C2=O)C4=C1C=CC=C4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ml-sa1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s9926-ml-sa1-chemical-structure.gif |