BSO
BSO is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ;-glutamylcysteine synthetase, γ;-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
| Trivial name | L-Buthionine sulfoximine, l-BSO |
| Catalog Number | S9728 |
| Molecular Formula | C8H18N2O3S |
| CAS# | 83730-53-4 |
| SMILES | CCCC[S](=N)(=O)CCC(N)C(O)=O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/bso-l-buthionine-s-r-sulfoximine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s9728-bso-l-buthionine-s-r-sulfoximine-chemical-structure.gif |