UNC6852
UNC6852 is a selective degrader that targets polycomb repressive complex 2 (PRC2) with IC50 of 247 nM for EED. UNC6852 is based on PROTAC and contains an EED226-derived ligand and a ligand for VHL.
Trivial name | N/A |
Catalog Number | S9659 |
Molecular Formula | C43H48N10O6S |
CAS# | 2688842-08-0 |
SMILES | CC1=C(SC=N1)C2=CC=C(CNC(=O)C3CC(O)CN3C(=O)C(NC(=O)CCCNC(=O)C4=CC=C(C=C4)C5=CN=C(NCC6=CC=CO6)[N]7C=NN=C57)C(C)(C)C)C=C2 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/unc6852.html |
Additional Information | https://file.selleck.cn/downloads/struct/s9659-unc6852-chemical-structure.gif |