Revumenib (SNDX-5613)
Revumenib(SNDX-5613) is a potent and selective inhibitor of menin-MLL binding with a Ki of 0.15 nM. SNDX-5613 shows anti-proliferative activity against multiple cell lines harboring MLLr translocations (MV4;11, RS4;11, MOLM-13, KOPN-8) with IC50 values ranging from 10-20 nM.
| Catalog Number | S8996 |
| Molecular Formula | C32H47FN6O4S |
| CAS# | 2169919-21-3 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CCN(C(C)C)C(=O)C1=C(OC2=CN=CN=C2N3CC4(CCN(CC4)CC5CCC(CC5)N[S](=O)(=O)CC)C3)C=CC(=C1)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sndx-5613.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s8996-sndx-5613-chemical-structure.gif |