BRD3308
BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.
Trivial name | N/A |
Catalog Number | S8962 |
Molecular Formula | C15H14FN3O2 |
CAS# | 1550053-02-5 |
SMILES | CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)F)N |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/brd3308.html |
Additional Information | https://file.selleck.cn/downloads/struct/BRD3308-chemical-structure-s8962.gif |