Olutasidenib
Olutasidenib is a potent, orally bioavailable, brain penetrant and selective mutant IDH1 (mIDH1) inhibitor with IC50 of 21.1 nM, 114 nM for IDH1-R132H, IDH1-R132C, respectively.
| Trivial name | FT-2102 |
| Catalog Number | S8949 |
| Molecular Formula | C18H15ClN4O2 |
| CAS# | 1887014-12-1 |
| Inchi | InChI=1S/C18H15ClN4O2/c1-10(21-16-6-4-13(9-20)23(2)18(16)25)14-8-11-7-12(19)3-5-15(11)22-17(14)24/h3-8,10,21H,1-2H3,(H,22,24)/t10-/m0/s1 |
| Inchi Key | NEQYWYXGTJDAKR-JTQLQIEISA-N |
| SMILES | CC(C1=CC2=C(C=CC(=C2)Cl)NC1=O)NC3=CC=C(N(C3=O)C)C#N |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/olutasidenib-ft-2102.html |
| Additional Information | https://file.selleck.cn/downloads/struct/olutasidenib-ft-2102-chemical-structure-s8949.gif |