Adagrasib (MRTX849)

Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.

Price Not Available 1g Adagrasib (MRTX849) Supplier Page

Trivial name	N/A
Catalog Number	S8884
Molecular Formula	C32H35ClFN7O2
CAS#	2326521-71-3
Inchi	InChI=1S/C32H35ClFN7O2/c1-21(34)31(42)41-17-16-40(18-23(41)11-13-35)30-25-12-15-39(28-10-4-7-22-6-3-9-26(33)29(22)28)19-27(25)36-32(37-30)43-20-24-8-5-14-38(24)2/h3-4,6-7,9-10,23-24H,1,5,8,11-12,14-20 H2,2H3/t23-,24-/m0/s1
Inchi Key	PEMUGDMSUDYLHU-ZEQRLZLVSA-N
SMILES	CN1CCCC1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN(C(C6)CC#N)C(=O)C(=C)F
Size	1g
Supplier Page	http://www.selleckchem.com/products/mrtx849.html
Additional Information	https://file.selleck.cn/downloads/struct/mrtx849-chemical-structure-s8884.gif