PLX5622
PLX5622 is a highly selective CSF-1R inhibitor (IC50 < 10 nmol/L), showing > 20-fold selectivity over KIT and FLT3.
| Trivial name | N/A |
| Catalog Number | S8874 |
| Molecular Formula | C21H19F2N5O |
| CAS# | 1303420-67-8 |
| Inchi | InChI=1S/C21H19F2N5O/c1-12-5-17-14(9-26-20(17)25-8-12)6-13-3-4-18(28-19(13)23)24-10-15-7-16(22)11-27-21(15)29-2/h3-5,7-9,11H,6,10H2,1-2H3,(H,24,28)(H,25,26) |
| Inchi Key | NSMOZFXKTHCPTQ-UHFFFAOYSA-N |
| SMILES | CC1=CC2=C(NC=C2CC3=C(N=C(C=C3)NCC4=C(N=CC(=C4)F)OC)F)N=C1 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/plx5622.html |
| Additional Information | https://file.selleck.cn/downloads/struct/plx5622-chemical-structure-s8874.gif |