Almonertinib (HS-10296)
Almonertinib (HS-10296) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
Trivial name | Aumolertinib |
Catalog Number | S8817 |
Molecular Formula | C30H35N7O2 |
CAS# | 1899921-05-1 |
Inchi | InChI=1S/C30H35N7O2/c1-6-29(38)32-24-17-25(28(39-5)18-27(24)36(4)16-15-35(2)3)34-30-31-14-13-23(33-30)22-19-37(20-11-12-20)26-10-8-7-9-21(22)26/h6-10,13-14,17-20H,1,11-12,15-16H2,2-5H3,(H,32,38)(H,31, 33,34) |
Inchi Key | DOEOECWDNSEFDN-UHFFFAOYSA-N |
SMILES | CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OC |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/hs-10296.html |
Additional Information | https://file.selleck.cn/downloads/struct/hs-10296-chemical-structure-s8817.gif |