PF-06873600
PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2), CDK4, and CDK6 with Ki values of 0.1, 1.2, and 0.1 nM, respectively, blocks the phosphorylation of retinoblastoma protein (RB1), and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM, respectively.
Trivial name | N/A |
Catalog Number | S8816 |
Molecular Formula | C20H27F2N5O4S |
CAS# | 2185857-97-8 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/pf-06873600.html |
Additional Information | https://file.selleck.cn/downloads/struct/s8816-pf-06873600-chemical-structure.gif |