Tinostamustine(EDO-S101)

Tinostamustine(EDO-S101) is a first-in-class alkylating deacetylase inhibitor with IC50 values of 9 nM, 9 nM, 25 nM and 107 nM for HDAC1, HDAC2, HDAC3 and HDAC8 (Class 1 HDACs) respectively and 6 nM, 72 nM for HDAC6 and HDAC10 (Class II HDACs).

Trivial name N/A
Catalog Number S8769
Molecular Formula C19H28Cl2N4O2
CAS# 1236199-60-2
Inchi InChI=1S/C19H28Cl2N4O2/c1-24-17-9-8-15(25(12-10-20)13-11-21)14-16(17)22-18(24)6-4-2-3-5-7-19(26)23-27/h8-9,14,27H,2-7,10-13H2,1H3,(H,23,26)
Inchi Key GISXTRIGVCKQBX-UHFFFAOYSA-N
SMILES CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCCCCC(=O)NO
Size 1g
Supplier Page http://www.selleckchem.com/products/tinostamustine.html
Additional Information https://file.selleck.cn/downloads/struct/tinostamustine-edo-S101-chemical-structure-s8769.gif