Tinostamustine(EDO-S101)
Tinostamustine(EDO-S101) is a first-in-class alkylating deacetylase inhibitor with IC50 values of 9 nM, 9 nM, 25 nM and 107 nM for HDAC1, HDAC2, HDAC3 and HDAC8 (Class 1 HDACs) respectively and 6 nM, 72 nM for HDAC6 and HDAC10 (Class II HDACs).
Trivial name | N/A |
Catalog Number | S8769 |
Molecular Formula | C19H28Cl2N4O2 |
CAS# | 1236199-60-2 |
Inchi | InChI=1S/C19H28Cl2N4O2/c1-24-17-9-8-15(25(12-10-20)13-11-21)14-16(17)22-18(24)6-4-2-3-5-7-19(26)23-27/h8-9,14,27H,2-7,10-13H2,1H3,(H,23,26) |
Inchi Key | GISXTRIGVCKQBX-UHFFFAOYSA-N |
SMILES | CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCCCCC(=O)NO |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/tinostamustine.html |
Additional Information | https://file.selleck.cn/downloads/struct/tinostamustine-edo-S101-chemical-structure-s8769.gif |