Abrocitinib (PF-04965842)
Abrocitinib (PF-04965842) is a potent JAK1 inhibitor with IC50s of 29 nM, 803 nM, > 10 000 nM and 1250 nM for JAK1, JAK2, JAK3 and tyrosine kinase (TYK) 2, respectively.
Trivial name | N/A |
Catalog Number | S8765 |
Molecular Formula | C14H21N5O2S |
CAS# | 1622902-68-4 |
Inchi | InChI=1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+ |
Inchi Key | IUEWXNHSKRWHDY-PHIMTYICSA-N |
SMILES | CCCS(=O)(=O)NC1CC(C1)N(C)C2=NC=NC3=C2C=CN3 |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pf-04965842.html |
Additional Information | https://file.selleck.cn/downloads/struct/04965842-chemical-structure-pf-s8765.gif |