Reparixin (Repertaxin)
Reparixin (Repertaxin, DF 1681Y) is a potent and specific inhibitor of CXCR1 with IC50 of 1 nM. Reparixin (Repertaxin) inhibits PMN migration induced by CXCL8 (IC50 = 1 nM) and rodent PMN chemotaxis induced by CXCL1 and CXCL2. Repertaxin inhibits the response of human PMN to CXCL1, which interacts with CXCR2 (IC50 = 400 nM).
| Trivial name | DF 1681Y |
| Catalog Number | S8640 |
| Molecular Formula | C14H21NO3S |
| CAS# | 266359-83-5 |
| Inchi | InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1 |
| Inchi Key | KQDRVXQXKZXMHP-LLVKDONJSA-N |
| SMILES | CC(C)CC1=CC=C(C=C1)C(C)C(=O)NS(=O)(=O)C |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/reparixin-repertaxin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/reparixin-repertaxin-chemical-structure-s8640.gif |