Pamiparib
Pamiparib is a potent and selective inhibitor of PARP1 and PARP2 with IC50 values of 0.83 and 0.11 nM, respectively in biochemical assays. It shows high selectivity over other PARP enzymes.
| Trivial name | BGB-290 |
| Catalog Number | S8592 |
| Molecular Formula | C16H15FN4O |
| CAS# | 1446261-44-4 |
| Inchi | InChI=1S/C16H15FN4O/c1-16-3-2-4-21(16)7-11-13-12-9(15(22)20-19-11)5-8(17)6-10(12)18-14(13)16/h5-6,18H,2-4,7H2,1H3,(H,20,22)/t16-/m1/s1 |
| Inchi Key | DENYZIUJOTUUNY-MRXNPFEDSA-N |
| SMILES | CC12CCCN1CC3=NNC(=O)C4=C5C3=C2NC5=CC(=C4)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/bgb-290.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bgb-290-chemical-structure-s8592.gif |