RRx-001
RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase(G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity.RRx-001 is also a downregulator of the CD47- SIRPĪ± checkpoint pathway.
| Trivial name | N/A |
| Catalog Number | S8405 |
| Molecular Formula | C5H6BrN3O5 |
| CAS# | 925206-65-1 |
| Inchi | InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7,8(11)12)9(13)14/h1-3H2 |
| Inchi Key | JODKFOVZURLVTG-UHFFFAOYSA-N |
| SMILES | C1C(CN1C(=O)CBr)([N+](=O)[O-])[N+](=O)[O-] |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/rrx-001.html |
| Additional Information | https://file.selleck.cn/downloads/struct/rrx-001-chemical-structure-s8405.gif |