WNK463
WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4) with IC50 of 5nM, 1nM, 6nM, and 9nM.
| Trivial name | N/A |
| Catalog Number | S8358 |
| Molecular Formula | C21H24F3N7O2 |
| CAS# | 2012607-27-9 |
| Inchi | InChI=1S/C21H24F3N7O2/c1-20(2,3)27-17(32)15-11-25-12-31(15)14-6-8-30(9-7-14)16-5-4-13(10-26-16)18-28-29-19(33-18)21(22,23)24/h4-5,10-12,14H,6-9H2,1-3H3,(H,27,32) |
| Inchi Key | HWSHOMMVLGBIDN-UHFFFAOYSA-N |
| SMILES | CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/wnk463.html |
| Additional Information | https://file.selleck.cn/downloads/struct/wnk463-chemical-structure-s8358.gif |