SBI-0640756
SBI-0640756(SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. It can also suppress AKT and NF-κB signaling.
| Trivial name | SBI-756 |
| Catalog Number | S8181 |
| Molecular Formula | C23H14ClFN2O2 |
| CAS# | 1821280-29-8 |
| Inchi | InChI=1S/C23H14ClFN2O2/c24-16-7-8-19-18(11-16)21(15-4-2-1-3-5-15)22(23(29)27-19)20(28)9-6-14-10-17(25)13-26-12-14/h1-13H,(H,27,29)/b9-6+ |
| Inchi Key | VVWGPQZBDQVQRC-RMKNXTFCSA-N |
| SMILES | C1=CC=C(C=C1)C2=C(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)C=CC4=CC(=CN=C4)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/sbi-0640756.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sbi-0640756-chemical-structure-s8181.gif |