Chaetocin
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
| Trivial name | N/A |
| Catalog Number | S8068 |
| Molecular Formula | C30H28N6O6S4 |
| CAS# | 28097-03-2 |
| Inchi | InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32, 37-38H,11-14H2,1-2H3/t19-,20-,25+,26+,27+,28+,29+,30+/m1/s1 |
| Inchi Key | PZPPOCZWRGNKIR-PNVYSBBASA-N |
| SMILES | CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/chaetocin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/chaetocin-chemical-structure-selleck.gif |