Sabutoclax
Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
| Trivial name | BI-97C1 |
| Catalog Number | S8061 |
| Molecular Formula | C42H40N2O8 |
| CAS# | 1228108-65-3 |
| Inchi | InChI=1S/C42H40N2O8/c1-21-15-27-29(17-31(45)39(49)35(27)41(51)43-19-23(3)25-11-7-5-8-12-25)37(47)33(21)34-22(2)16-28-30(38(34)48)18-32(46)40(50)36(28)42(52)44-20-24(4)26-13-9-6-10-14-26/h5-18,23-24,45 -50H,19-20H2,1-4H3,(H,43,51)(H,44,52)/t23-,24-/m0/s1 |
| Inchi Key | RAYNZUHYMMLQQA-ZEQRLZLVSA-N |
| SMILES | CC1=CC2=C(C(=C(C=C2C(=C1C3=C(C4=CC(=C(C(=C4C=C3C)C(=O)NCC(C)C5=CC=CC=C5)O)O)O)O)O)O)C(=O)NCC(C)C6=CC=CC=C6 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/sabutoclax.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Sabutoclax-BI-97C1-chemical-structure-s8061.gif |