Larotrectinib sulfate

Larotrectinib sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.

Price Not Available 1g Larotrectinib sulfate Supplier Page

Trivial name	LOXO-101 sulfate, ARRY-470 sulfate
Catalog Number	S7960
Molecular Formula	C21H22F2N6O2.H2SO4
CAS#	1223405-08-0
Inchi	InChI=1S/C21H22F2N6O2.H2O4S/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27;1-5(2,3)4/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31);(H2,1,2,3,4)/t1 4-,18+;/m0./s1
Inchi Key	PXHANKVTFWSDSG-QLOBERJESA-N
SMILES	C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O
Size	1g
Supplier Page	http://www.selleckchem.com/products/loxo-101.html
Additional Information	https://file.selleck.cn/downloads/struct/loxo-101-chemical-structure-s7960.gif