SBI-0206965
SBI-0206965 is a highly selective autophagy kinase ULK1 inhibitor with IC50 of 108 nM, about 7-fold selectivity over ULK2. SBI-0206965 inhibits autophagy and enhances apoptosis in human glioblastoma and lung cancer cells.
| Trivial name | N/A |
| Catalog Number | S7885 |
| Molecular Formula | C21H21BrN4O5 |
| CAS# | 1884220-36-3 |
| Inchi | InChI=1S/C21H21BrN4O5/c1-23-19(27)13-7-5-6-8-15(13)31-20-14(22)11-24-21(26-20)25-12-9-16(28-2)18(30-4)17(10-12)29-3/h5-11H,1-4H3,(H,23,27)(H,24,25,26) |
| Inchi Key | NEXGBSJERNQRSV-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/sbi-0206965.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sbi-0206965-chemical-structure-s7885.gif |