Eliglustat
Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.
| Trivial name | GENZ-112638 |
| Catalog Number | S7852 |
| Molecular Formula | C23H36N2O4 |
| CAS# | 491833-29-5 |
| Inchi | InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26)/t19-,23-/m1/s1 |
| Inchi Key | FJZZPCZKBUKGGU-AUSIDOKSSA-N |
| SMILES | CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/eliglustat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/eliglustat-tartrate-chemical-structure-s7852.gif |