Tretazicar (CB1954)
Tretazicar (CB1954) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.
| Trivial name | NSC 115829 |
| Catalog Number | S7829 |
| Molecular Formula | C9H8N4O5 |
| CAS# | 21919-05-1 |
| Inchi | InChI=1S/C9H8N4O5/c10-9(14)5-3-7(11-1-2-11)8(13(17)18)4-6(5)12(15)16/h3-4H,1-2H2,(H2,10,14) |
| Inchi Key | WOCXQMCIOTUMJV-UHFFFAOYSA-N |
| SMILES | C1CN1C2=C(C=C(C(=C2)C(=O)N)[N+](=O)[O-])[N+](=O)[O-] |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/cb1954.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cb1954-chemical-structure-s7829.gif |